Aamir Zuberi, PhD is a Technology and Resource Development Scientist and the leader of the Rare and Orphan Disease Program, The Jackson Laboratory, Bar Harbor. In this position he has developed more than 200 new mouse models in the last five years using CRISPR/Cas9, embryonic stem cell and transgenic strategies. These include mice with fully defined alterations in the spermine synthase gene on defined genetic backgrounds. These serve as much better models for SRS than a previous mouse model which was produced by whole body irradiation that deleted the spermine synthase and an adjacent gene on a mixed background. He will discuss these mice in his presentation and they are being used for research by several others presenters.

Aamir has a PhD in Microbial Molecular Genetics from the University of Sheffield, UK. He has more than 25 years of experience in molecular biology, genome manipulation and murine molecular genetics.